Profession

Tumor Immunologist, Cancer Biologist

Appointments

Adjunct Research Professor

Department of Oncology 

Western University

 

Website

Research Group

Other

Research Interest Area 

Cancer
Immunotherapy
Microbiome

Research Overview

Dr. Maleki’s research is focused on understanding how to sensitize hard-to-treat cancers to immunotherapy with immune checkpoint inhibitors. Dr. Maleki’s main focus is to induce neoantigen formation in tumor cells by blocking their DNA repair pathways.

Dr. Maleki is also interested in translating promising pre-clinical Immuno-Oncology studies into early phase I clinical studies. He collaborates with medical oncologists, surgical oncologists, and radiation oncologists at the London Regional Cancer Program to organize such early clinical studies. Dr. Maleki is currently leading a multidisciplinary team of clinicians and scientists that are organizing a phase I study on combination of Fecal Microbial Transplant (FMT) with immunotherapy in melanoma patients.

Dr. Maleki’s is a member of the city-wide melanoma/skin disease site team. His clinical interest also involves renal cell carcinoma, head and neck cancer, lung cancer, and breast cancer.

Keywords

Immunotherapy, Oncology, Drug Development, Hard-to-treat cancers, Microbiome, Cancer

Partners

Other Professional Roles and Affiliations

President and Founder

Zealous Scientifics Inc. (2014-2018)