Biography

• Distinguished Oncology Scientist of the London Regional Cancer Program (the LRCP, at the London Health Sciences Centre)

• Director, Strategic Training Program in Cancer Research and Technology Transfer (CaRTT, funded by the London Regional Cancer Program, Western Department of Oncology, the Lawson Health Research Institute, and Western’s Schulich School of Medicine and Dentistry). CaRTT is the home of “Partners in Experiential Learning”, a curriculum-based program for high-achieving high school students to usher them into training for leadership positions in science, technology, engineering, mathematics, and medical research. Koropatnick works with Rodger Dusky (PEL Director) to deliver the program

• Chief Scientific Officer and co-founder (with Dr. Mark Vincent) of Sarissa, Inc. (a biotech discovery company)

• Scientific Advisory Board Member, Critical Outcomes Therapeutics, Inc., Formation Biologics, Inc., Zealous Therapeutics, Inc., and MedVax Pharma, Inc.

• Queen Elizabeth II Golden Jubilee Medal (2002)

• Schulich School of Medicine and Dentistry Dean’s Award of Excellence (2007)

UWO Dept. of Oncology, Excellence in Teaching Award (2005)

UWO Dept. of Oncology, Excellence in Teaching and Research Award (2009)

Professional and Academic Experience

• Assist. Director, Lawson (2007-present)

• Director, CaRTT (Training Program in Cancer Research and Technology Transfer)(2004-present)

• Director, Cancer Research Laboratory Program, London Health Sciences Centre (1999-2015)

• Full Prof. (1996-present), Assoc. Prof. (1988-96), Assist. Prof. (1984-88), Dept. of Oncology, Univ. Western Ont. (cross-appointed, Depts. of Pathology, Microbiol/Immunol, Phys/ Pharm)(1996-present)

• Career Scientist, Cancer Care Ontario (1988-04), Ontario Cancer Treatment and Research Foundation (1984-88)

PDF, Alberta Medical Heritage Foundation, University of Calgary, Alberta (1980-84)

• PhD, Genetics (1980), MSc, Genetics (1978), BSc, Biochemistry (1974), University of British Columbia

• Peer review panels: Canadian Institutes of Health Research (1992-95, Fellowships “B”; 1997-00, Pharmaceutical Sciences; 2001-02, 2005, 2013-14, Pharmacology and Toxicology; 2006-11, Pharmaceutical Sciences [Panel Chair, 2008-11]; 2015-16, Doctoral Research Awards “A”; Virtual Chair, Open Operating Grants Competition, 2016 National Cancer Institute of Canada (2004-07, Panel G: Exp. Therapeutics, Medicinal Chemistry and Carcinogenesis; 2004-09, Panel G: Exp. Therapeutics, Medicinal Chemistry, and Carcinogenesis; 2005-06, Panel G2: Carcinogenesis, DNA Damage & DNA Repair [Panel Chair, 2007-2009]) CBCF (2006-14, Fellowships) US-EPA (1997, EPA/AWWARF/ACWA Joint Solicitation for Arsenic Research)

• Citations: 3720 (1491 since 2011), h-index: 32, i10-index: 75

Profession

Cancer Scientist

Administrative Support

Lindsay Seitz (x53264)

Research Group

Research Interest Area 

Cancer
Drug discovery and development
Immune system/disorders

Research Overview

a) Discovery and development of novel antisense and small molecule drugs that enhance the effectiveness of current approved anticancer chemotherapy (funded by the Canadian Institutes of Health Research [CIHR] and the Medical Oncology Research Fund [MORF])

b) Discovery and development of novel anticancer compounds based on in silico targeting prediction (in collaboration with and funded by Critical Outcome Technologies, Inc.)

c) Discovery and development of novel antibodies and antibody-drug conjugates for treatment of breast, colorectal, head and neck, and other cancers (in collaboration with and funded by Formation Biologics, Inc., the Ontario Centres of Excellence TPS and C2C Programs, and the Ontario Research Fund-Ontario Preclinical Imaging Consortium [ORF-OPIC])

d) Discovery and development of novel immunotherapeutic drugs to stimulate innate immunity against human cancers (in collaboration with and funded by Trillium Therapeutics, Inc.)

Publications

Keywords

Drug Development, Immunotherapy, Imaging, Antisense

Partners

Trillium Therapeutics, Inc.

Formation Biologics, Inc.

Critical Outcome Technologies, Inc.

Al-Quds University, Israel

MD Anderson Cancer Center

Univ. of Arizona Beyond Center