Biography

Dr Lala has published over 206 peer-reviewed articles and 360 conference abstracts. . He served on the editorial board of numerous reputed Biomedical journals such as the Experimental Hematology, Leukemia research, American journal of Anatomy, American journla of Reproductive Immunology, Placenta, Biology of Reproduction, cancer Metastasis Reviews.   He received long term funding from the Medical Research Council of Canada (currently renamed CIHR) and the National cancer Institute of Canada (currently renamed CCSRI), and substantial funding from other agencies such as the NIH -USA, US-DOD (Breast Cancer Program), Lalor Foundation USA, Cancer Research Society, The Breast Caner Society of Canada, the Canadian Breast Cancer Foundation and the Ontario Institute of Cancer research. He served on the grants review panels of the MRC (CIHR), NIH (USA), NCIC, CRS, Cannaught Foundation and the CBCF, and also as an external reviewer to the US-Israel Science and Technology Foundation, cancer Research campaign (UK), Austrian science Foundation, Swiss National Foundation, AIRC, Itay, Welcome Foundation, UK, sheffield Hospital charitable Trust,  Cambridge University Research Funds, and a s a member of the Site Visit teams of the NIH. He has served as the President of the Canadian Association of Anatomists, Cell Biologists and Neurobiologists, the Vice President of the American Society of reproductive Immunology and a founding member and organizer of the International Federation of Placental associations (IFPA) Meetings. He has been a plenary speaker at many internationla meetings in Reproduction and Cancer. 

Dr Lala has received many prestigious awards including the J.C.B. Grant Senior Scientist award of the Canadian Association of Anatomists, Cell Biologists and Neurobiologists (1990), and Research Excellence Award of the Faculty of Medicine, UWO (1996). In 2001, he was honoured by his peers and past trainees with an international symposium at Queens University, sponsored by the CIHR, held in tribute to his unique contributions building the bridge between the fields of reproductive and cancer biology. For his five decades of outstanding contributions to biomedical research and education, in June 2013, the University of Western Ontario  bestowed  its highest honor to Dr Lala by awarding him the Doctor of Science degree, honoris causa at its annual convocation where he addressed the graduating students receiving their undergraduate and graduate degrees in bio-medical sciences (video).

Professional and Academic Experience

Following a short period of teaching career in Pathology in Calcutta University (1959-1962), Dr. Lala started his independent research career in 1963 at the Argonne National Laboratory in USA wherefrom he moved as a faculty member at the University of California Medical Centre in San Francisco (1964). In 1967, he moved to Canada initially as a research scientist at the Chalk River Nuclear Laboratories and then a faculty member at the Department of Anatomy & Cell Biology, McGill University in Montreal (1968), where he became a full professor in 1977. In 1983, he relocated to the University of Western Ontario as the Chair of the Department of Anatomy & Cell Biology (1983-1993). He is also cross-appointed at the Department of Oncology since 1990. Currently he is a Professor-emeritus with a fully active, well-funded research lab and some teaching responsibilities for senior medical students. He has trained some forty-five graduate students and eighteen post-doctoral fellows many of whom are independent scientists.

Profession

Professor

Website

Research Group

Research Interest Area 

Fetal and Newborn Health
Reproduction and pregnancy

Research Overview

Research in his laboratory investigates cellular and molecular mechanisms at the fetal-maternal interface responsible for human placental development in health and disease, and those responsible for invasion and metastasis in breast cancer with a goal to prevent certain fetal-maternal maladies, and to develop new modes of breast cancer therapy.

Research Focus:

  • Development of the human placenta
  • Placental influence on the fetus and the newborn
  • Intra-uterine growth restriction of the fetus
  • Preeclampsia
  • Breast cancer
  • Molecular targets for breast cancer therapy, prevention and intervention
  • Prevention of breast cancer metastasis.

See news coverage from Dr. Lala’s latest discovery, expected to have significant impact on maternal, fetal and neonatal health:

CTV London: Maternal Health

The Londoner: Western researchers close in on breakthrough in maternal, fetal and neonatal health

Publications

Keywords

breast cancer, Placenta, Decorin, Cancer Stem cells, Cyclo-oxygenase-2, Trophoblast, Preeclampsia, lymphangiogenesis

Partners

Drs david hess, Victor Han, Lynne Postovit, Genevieve eastabrook, Barbra de Vrijer, Ann Chambers